====== Transpedicular corpectomy ====== ===== Case series ===== In a single-center [[Humanitas Research Hospital]], retrospective study. Demographics, clinical, and radiologic data of 19 patients who underwent surgery for [[thoracolumbar burst fracture]]s between 2016 and 2019 were collected. All patients enrolled in the present study underwent surgery by means of posterior fixation and [[transpedicular]] [[corpectomy]] with the aid of an intraoperative image-guided [[neuronavigation]] system. Postoperative correction of the vertebral height ratio was achieved in all cases, with an average increase of 23.6% (p = 0.0005). No statistical differences (p = 0.9) were found comparing 1- and 3-month postoperative CT scans, in relation to vertebral height ratio. A statistically significant difference was found between the pre-and postoperative kyphotic angles for the thoracolumbar and lumbar segments (p = 0.0018 and 0.005, respectively), but no difference was found between kyphotic angles at the 3-month follow-up. A unilateral approach was performed on 15 patients (79%), while 4 cases (21%) required a bilateral laminectomy. We did not observe any significant intraoperative complications. Single-stage posterior corpectomy and fixation is a safe and effective approach for thoracic and lumbar burst fractures. It provides excellent 360-degree reconstruction in a single surgical stage with satisfactory results in terms of kyphosis reduction, biomechanical stability, and reduced invasiveness. Spinal navigation represents a fundamental tool to overcome some anatomical limits of the presented technique ((Anania CD, Bono BC, Tropeano M, Fornari M, Servadei F, Costa F. Single-Stage Posterior Transpedicular Corpectomy and 360-Degree Reconstruction for Thoracic and Lumbar Burst Fractures: Technical Nuances and Outcomes. J Neurol Surg A Cent Eur Neurosurg. 2022 Apr 6. doi: 10.1055/s-0042-1743515. Epub ahead of print. PMID: 35388449.)).