====== Therapeutic Enthusiasm ====== Therapeutic [[enthusiasm]] refers to the premature or exaggerated [[optimism]] about the clinical potential of a treatment or molecular target, often based on limited, early-stage, or preclinical evidence. 🧪 In research contexts: It usually manifests when authors or scientists: Overstate the translational relevance of a molecular finding Propose therapeutic applications without sufficient validation in humans Ignore biological complexity, safety, or feasibility āš ļø Why it's problematic: Therapeutic enthusiasm can: Mislead readers, funders, or clinicians Fuel hype cycles that later collapse Undermine [[scientific credibility]] when results fail to translate In short: Therapeutic enthusiasm turns a petri dish into a miracle cure—on paper.