====== Thalamic prefrontal peduncle ======
The thalamic-[[prefrontal peduncle]] (TPP) is a large [[bundle]] connecting the [[thalamus]] and [[prefrontal cortex]]. 

===== Function =====

The definitive structure and function of the TPP are still controversial. To investigate the [[connectivity]] and [[segmentation]] patterns of the TPP, Sun et al., employed [[DSI]] diffusion spectrum imaging with [[Generalized q-sampling imaging]] reconstruction to perform both subject-specific and template-based analyses. 

The results confirmed the trajectory and spatial relationship of the TPP in the human brain and identified the connection areas in the [[prefrontal cortex]]. The TPP-connecting areas identified based on [[Brodmann area]]s (BAs) were BAs 8-11 and 45-47. Based on the automated anatomical atlas, these areas were the medial superior frontal gyrus, [[superior frontal gyrus]], [[middle frontal gyrus]], [[pars triangularis]], [[pars orbitalis]], anterior [[orbital gyrus]], and lateral orbital gyrus. In addition, they identified the TPP connection areas in the [[thalamus]], including the anterior and medial nuclei, and the lateral dorsal/lateral posterior nuclei. TPP fibers connected the thalamus with the ipsilateral prefrontal BAs 11, 47, 10, 46, 45, 9, and 8 seriatim from medial to lateral, layer by layer. Our results provide further details of the thalamic-prefrontal peduncle structure, and may aid future studies and a better understanding of the functional roles of the TPP in the human brain
((Sun C, Wang Y, Cui R, Wu C, Li X, Bao Y, Wang Y. Human Thalamic-Prefrontal
Peduncle Connectivity Revealed by Diffusion Spectrum Imaging Fiber Tracking.
Front Neuroanat. 2018 Apr 17;12:24. doi: 10.3389/fnana.2018.00024. eCollection
2018. PubMed PMID: 29719502; PubMed Central PMCID: PMC5913328.
)).