====== Temozolomide desensitization ======


There are minimal [[report]]s of [[temozolomide]]-induced [[DRESS syndrome]]. The diagnosis can be life-threatening, which makes the [[glioblastoma treatment]] with no alternative treatment option challenging. The use of [[temozolomide desensitization]] has been proposed for the management of severe adverse [[cutaneous drug reaction]]s
((Ambur A, Ambur L, Khan L, Nathoo R. Drug-induced hypersensitivity syndrome following temozolimide for glioblastoma multiforme and the role of desensitization therapy. J Oncol Pharm Pract. 2022 Apr;28(3):733-735. doi: 10.1177/10781552211062569. Epub 2021 Nov 26. PMID: 34825610.)).