**Superior Vena Cava Syndrome (SVCS)** is a **medical emergency** caused by **obstruction of blood flow through the superior vena cava (SVC)** โ€” the major vein that drains blood from the head, neck, upper chest, and upper limbs into the heart. --- ### ๐Ÿง  **Etiology (Causes):** Most common cause: - **Malignancy (โ‰ˆ 85%)**, especially: - **Lung cancer** (especially small cell) - **Non-Hodgkin lymphoma** - **Metastatic cancers (e.g., breast, testicular)** Other causes: - **Thrombosis** (especially from **central venous catheters or pacemaker wires**) - **Fibrosing mediastinitis** - **Aortic aneurysm or goiter compressing the SVC** --- ### ๐Ÿฉบ **Clinical Features:** Symptoms result from **impaired venous return** from the upper body: - **Facial swelling or fullness** - **Neck and upper limb swelling** - **Distended veins** on chest wall or neck - **Dyspnea**, cough, orthopnea - **Headache, dizziness, visual disturbances** - **Hoarseness** or **dysphagia** (due to local compression) - **Stridor** (if airway is compressed) Symptoms may be **worse when lying down**. --- ### ๐Ÿงช **Diagnosis:** - **Clinical suspicion** from history and exam - **Chest X-ray**: may show mediastinal widening or mass - **CT scan with contrast**: preferred imaging to confirm compression or thrombus - **MRI or venography**: alternative if CT is contraindicated - **Biopsy** if malignancy suspected --- ### ๐Ÿ’‰ **Management:** Depends on **underlying cause and severity**: #### ๐Ÿ”น Supportive: - Elevate head of bed - Oxygen - Corticosteroids (if lymphoma suspected) - Diuretics (to reduce edema) #### ๐Ÿ”น Specific: - **Radiation therapy** (often first-line if malignant) - **Chemotherapy** (especially in chemosensitive tumors like lymphoma) - **Endovascular stenting** (rapid symptom relief) - **Anticoagulation** if thrombosis --- ### โš ๏ธ Emergency Features: - Stridor - Laryngeal edema - Cerebral edema (confusion, decreased consciousness) These warrant **urgent intervention**, potentially **airway management** and **stenting**.