The description of human white matter [[pathway]]s experienced a tremendous improvement, thanks to the advancement of [[neuroimaging]] and [[dissection]] techniques. The downside of this progress is the production of redundant and conflicting [[literature]], bound by specific studies' methods and aims. The [[Superior Longitudinal System]] (SLS), encompassing the [[arcuate]] (AF) and the [[superior longitudinal fasciculi]] (SLF), becomes an illustrative example of this fundamental issue, being one of the most studied white matter association pathways of the brain. Vavassori et al. provided a complete illustration of this white matter fiber system's current definition, from its early descriptions in the nineteenth century to its most recent characterizations. They proposed a review of both [[in vivo]] [[diffusion magnetic resonance imaging]]-based [[tractography]] and anatomical dissection studies, enclosing all the information available up to date. Based on these findings, they reconstructed the wiring diagram of the SLS, highlighting a substantial variability in the description of its cortical sites of termination and the taxonomy and partonomy that characterize the system. They aimed to level up discrepancies in the [[literature]] by proposing a parallel across the various [[nomenclature]]. Consistent with the topographical arrangement already documented for commissural and projection pathways, they suggested approaching the SLS organization as an orderly and continuous wiring [[diagram]], respecting a medio-lateral palisading [[topography]] between the different [[frontal]], [[parietal]], [[occipital]], and [[temporal]] [[gyri]] rather than in terms of individualized fascicles. A better and complete description of the fine organization of [[white matter]] association pathways' [[connectivity]] is fundamental for a better understanding of brain function and their clinical and neurosurgical applications
((Vavassori L, Sarubbo S, Petit L. Hodology of the superior longitudinal system of the human brain: a historical perspective, the current controversies, and a proposal. Brain Struct Funct. 2021 Apr 21. doi: 10.1007/s00429-021-02265-0. Epub ahead of print. PMID: 33881634.)).