====== Spinal infection risk factors ====== [[Risk factor]]s for developing [[spinal infection]] include conditions that compromise the immune system, such as: Advanced age Intravenous drug use Human immunodeficiency virus (HIV) infection Long-term systemic usage of steroids Diabetes mellitus Organ transplantation Malnutrition Cancer Surgical risk factors include surgeries of long duration, high blood loss, implantation of instrumentation and multiple, or revision, surgeries at the same site. Infections occur in 1-4% of surgical cases, despite numerous preventative measures that are followed. ---- [[Spinal infection]]s in [[People who inject drugs]] are an underreported serious medical complication of injecting drug use. Though [[mortality]] is low, there is significant [[morbidity]] with prolonged [[admission]]s, large antimicrobial requirements and surgical interventions generating a substantial [[cost]] to the [[health system]] ((Ananda RA, Attwood LO, Lancaster R, Jacka D, Jhoomun T, Danks A, Woolley I. The Clinical and Financial Burden of Spinal Infections in People who Inject Drugs. Intern Med J. 2021 May 24. doi: 10.1111/imj.15397. Epub ahead of print. PMID: 34028966.)).