====== Sodium-23 (²³Na) ====== Sodium-23 (²³Na) is the only stable and naturally occurring isotope of the chemical element sodium (Na). 🔬 Key Properties: Atomic number: 11 Mass number: 23 Spin: 3/2 (quadrupolar nucleus, which influences MRI signal behavior) Natural abundance: 100% of all sodium in the human body is ²³Na. 🧠 Medical Relevance: ²³Na is biologically essential, playing a critical role in: Maintaining osmotic balance Cell membrane potential Neuronal signaling Muscle contraction In MRI, ²³Na nuclei can be detected using sodium MRI (²³Na-MRI), allowing the assessment of tissue sodium concentration (TSC), which is linked to cell viability, edema, and tumor physiology. 🧪 Summary: Sodium-23 is the MRI-detectable isotope of sodium that serves as a window into the cellular microenvironment, particularly useful in research and emerging clinical imaging techniques like ²³Na-MRI.