====== Skull base meningioma epidemiology ======


[[Skull base meningioma]]s represent approximately 25% of all [[meningioma]]s, nearly 20% of which are [[atypical meningioma]] or [[anaplastic meningioma]].

As with [[intracranial meningioma]]s in other regions, [[skull base]] meningiomas demonstrate a [[female]] predominance, with a female-to-[[male]] ratio as high as 3:1.

Approximately 15% of meningiomas grow along the [[sphenoid ridge]], with 10% developing in the [[posterior cranial fossa]] and 5% in the [[olfactory groove]].

Meningiomas of the floor of the [[middle fossa]] are uncommon and tend to grow quite large before diagnosis.



Skull-base meningiomas are characterized by other recurrent mutations, including [[AKT]]1, [[SMO]], [[KLF4]], [[TRAF7]] and [[POLR2A]].