[[Cerebrospinal fluid shunt]] or [[device]]-associated [[infection]] are rare but with a high mortality rate. Mortality was more closely related to the [[infection]] than to [[comorbidity]] or underlying [[neurosurgical disease]]. A second [[CSF]] [[analysis]] significantly helped to detect patients with device-associated infections with a poor prognosis ((Zeggay A, Patry I, Chirouze C, Bouiller K. Characteristics and outcomes of Cerebrospinal Fluid Shunt and Drain-Associated infections. Infect Dis Now. 2023 Jan 31:104665. doi: 10.1016/j.idnow.2023.104665. Epub ahead of print. PMID: 36736666.)) [[Children]]s with [[shunt infection]]s have an increased [[mortality]] rate and risk of [[seizure]] than those without [[shunt infection]]. Those with [[myelomeningocele]] who develop [[ventriculitis]] after [[shunt]]ing have a lower IQ compared to those without [[infection]] ((McLone D.G., Czyzewski D., Raimondi A.J.Central nervous system infections as a limiting factor in the intelligence of children with myelomeningocele. Pediatrics, 70 (1982), pp. 338-342.)). [[Mortality]] ranges from 10-15 %.