====== Search Strategy Template ======

=== 1. Identify Key Concepts ===
  * Break down your PICO into main concepts:
    - Population (P)
    - Intervention (I)
    - Comparator (C) — optional
    - Outcome (O) — optional

=== 2. List Keywords and Synonyms ===
  * For each concept, list keywords, synonyms, acronyms, and relevant subject headings (e.g., MeSH in PubMed).

=== 3. Use Boolean Operators ===
  * Use **OR** to combine synonyms within each concept.
  * Use **AND** to combine different concepts.
  * Use **NOT** carefully to exclude irrelevant terms.

=== 4. Apply Truncation and Wildcards ===
  * Use truncation symbols (e.g., * or $) to capture word variants.
  * Use wildcards for spelling variations.

=== 5. Adapt to Specific Databases ===
  * Modify syntax for each database (e.g., PubMed, Embase, Cochrane).
  * Use controlled vocabulary terms where available (e.g., MeSH, Emtree).

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====== Example Search Strategy for PubMed ======

**Research question:**  
_“Effectiveness of aspirin for preventing stroke in diabetic patients”_