====== Screening for glioma ====== At present, [[screening]] for [[glioma]]s has no clinical relevance. This is because of the low [[incidence]], the lack of sensitive biomarkers in [[plasma]], and the observation that gliomas may develop apparently de novo within few weeks or months. To the best of our knowledge, there is no routine use of a serum biomarker for clinical follow-up ((Linhares P, Carvalho B, Vaz R, Costa BM. Glioblastoma: Is There Any Blood Biomarker with True Clinical Relevance? Int J Mol Sci. 2020 Aug 13;21(16):5809. doi: 10.3390/ijms21165809. PMID: 32823572; PMCID: PMC7461098.)).