====== Rhino-Orbital-Cerebral Mucormycosis Treatment ====== {{rss>https://pubmed.ncbi.nlm.nih.gov/rss/search/1xONNp6hzwm9FuiF7i3Nk48rKg4eYx1fOXGHaksUHCpExpNs9E/?limit=15&utm_campaign=pubmed-2&fc=20250126160126}} === 1. Surgical Intervention === * **[[Debridement]]:** Aggressive removal of necrotic tissue. * **[[Orbital Exenteration]]:** Required in severe cases to prevent intracranial spread. === 2. Antifungal Therapy === * **Liposomal [[Amphotericin B]]:** First-line therapy (5–10 mg/kg/day). * **Step-Down Therapy:** [[Posaconazole]] or [[Isavuconazole]] for long-term management. === 3. Managing Underlying Conditions === * Tight control of blood [[glucose]] levels. * Reduce or discontinue [[corticosteroid]]s. === 4. Supportive Care === * Oxygen therapy for [[hypoxia]]. * Fluid and [[electrolyte]] management.