====== q4207 ====== 73-year-old patient, admitted for a infiltrative [[lesion]] highly suggestive of [[Primary leptomeningeal lymphoma]]. ===== Past Medical History ===== [[Hypercholesterolemia]] [[Depression]] [[Hydrocephalus]]. [[Endoscopic third ventriculostomy]] ==== Treatment ==== [[Simvastatin]] [[Desvenlafaxine]]. ===== History of the present illness ===== Abnormal [[gait]] with [[instability]] and a feeling of magnetism in it, accompanied by [[bradypsychia]] and occasional [[memory]] failures. ===== Test results ===== ==== MRI ==== {{::q4207mripreop.jpg?400|}} Regarding the last previous control, there are no significant variations, however, when comparing the evolution of the previous studies over the last 2 years, a constant progression is identified both in [[FLAIR]] and in the diffusion of [[periventricular]] predominance, especially at the right [[parietal]] level, with involvement of the [[splenium]] of the [[corpus callosum]] and in the right hemi[[protuberance]] in the last 2 studies, both in diffusion and in FLAIR, with a progressive increase in uptake, without clear images of [[mass effect]] at the current time. The lesion is highly suggestive of lymphoma.