=====PROSPERO===== https://www.crd.york.ac.uk/prospero/ International [[Prospective]] Register of [[Systematic Review]]s. ---- PROSPERO is an international [[database]] of [[prospective]]ly registered [[systematic review]]s in health and social care, welfare, public health, education, crime, justice, and international development, where there is a health related outcome. Key features from the [[review]] [[protocol]] are recorded and maintained as a permanent record. PROSPERO aims to provide a comprehensive listing of [[systematic review]]s registered at inception to help avoid duplication and reduce opportunity for reporting [[bias]] by enabling comparison of the completed review with what was planned in the protocol. PROSPERO is produced by CRD and funded by the [[National Institute for Health Research]] (NIHR). Systematic review protocols on PROSPERO can include any type of any study design. Reviews of reviews and reviews of methodological issues that contain at least one outcome of direct patient or clinical relevance are also accepted.