====== Primary central nervous system lymphoma chemotherapy ======

===== General information =====

For [[Primary central nervous system lymphoma]]:

In non-[[AIDS]] cases, [[chemotherapy]] combined with [[XRT]] prolongs survival compared to [[XRT]] alone.
((DeAngelis LM, Yahalom J, Heinemann M-H, et al. Primary Central Nervous System Lymphomas: Combined Treatment with Chemotherapy and Radiotherapy. Neurology. 1990; 40:80–86)).

===== Methotrexate (MTX) =====

see [[Methotrexate for primary central nervous system lymphoma]].


===== Rituximab =====

[[Rituximab]] is available since [[1997]] for the treatment of refractory systemic [[B-cell]] [[non-Hodgkin lymphoma]]. [[Intrathecal]]ly may be more effective for [[CD33]] + lymphomas.