A 7-year-old girl with unspecified [[T cell immunodeficiency]] presented with left-sided weakness and was found to have a right-sided frontal lobe mass on imaging. The mass was resected; histopathology and molecular studies evidenced diffuse large B-cell lymphoma. Prior chest imaging had revealed left upper lobe mass, and repeat chest imaging revealed multiple pulmonary nodules, initially concerning for metastasis. Video-assisted thoracoscopic surgical wedge resection of the lung mass was performed; the molecular profile was distinct from the PCNSL, suggesting synchronous de novo lymphomagenesis of brain and pulmonary primaries
((Ghali MGZ, Samkari A, Hou JS, Balasubramanian M, Besmer S, Keisling M, Narayan
P. Synchronous Primary Central Nervous System and Pulmonary Lymphoma in a
7-Year-Old Female with Unspecified T-Cell Immunodeficiency. Pediatr Neurosurg.
2018 Aug 15:1-6. doi: 10.1159/000490728. [Epub ahead of print] PubMed PMID:
30110687.
))
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A 41-year-old woman suffering from non-Hodgkin's B-cell primary lymphoma of the central nervous system involving both eyes. The article features the data on 85-month follow-up, as well as description of the clinical and instrumental features of the disease. The study provides analysis of the long-term results of combined treatment of recurrent primary intraocular lymphoma including repeated courses of radiation therapy in the N.N. Burdenko National Scientific and Practical Center for Neurosurgery, 16, 4 ,Tverskaya-Yamskaya St., [[Moscow]], Russian Federation.
((Tropinskaya OF, Vetlova ER, Serova NK, Golanov AV, Fil'chenkova NA.
[Multi-session stereotactic radiotherapy in the treatment of recurrent B-cell
primary intraocular lymphoma (a case report)]. Vestn Oftalmol. 2018;134(3):78-85.
doi: 10.17116/oftalma2018134378. Russian. PubMed PMID: 29953086.)).

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Therapeutic Outcomes and Toxicity of
High-Dose [[Methotrexate]]-Based Chemotherapy for Elderly Patients with Primary
Central Nervous System Lymphoma: A Report on Six Cases
((Tempaku A, Takahashi Y, Kamada H. Therapeutic Outcomes and Toxicity of
High-Dose Methotrexate-Based Chemotherapy for Elderly Patients with Primary
Central Nervous System Lymphoma: A Report on Six Cases. Acta Haematol. 2019 May
21:1-2. doi: 10.1159/000499100. [Epub ahead of print] PubMed PMID: 31112947.)).