Stereotactic intervention into the posterior hypothalamus gives satisfactory results for controlling both aggressive, violent behavioral disorders and intractable pain. From the endocrinological point of view, this procedure activates the hypothalamic-hypophyseal axis only temporarily, without causing any serious dysfunctions
((Mayanagi Y, Hori T, San K. The posteromedial hypothalamus and pain, behavior, with special reference to endocrinological findings. Appl Neurophysiol. 1978;41(1-4):223-31. doi: 10.1159/000102421. PMID: 365099.)).

see [[Posteromedial Hypothalamic Deep Brain Stimulation for Refractory Aggressiveness]]