====== PICOT ====== ([[Patient]], [[Intervention]], [[Comparative]], [[Outcome]], [[Timing]], and [[Type of study]]), complemented with a verification of [[regulatory approval]], examination of sample size, quality of patient allocation, maintenance of treatment, and presence of masking techniques The systematic review suggested in the methods section is: patients (P), regulatory approval, sample size calculation, allocation, intervention group (I), control group (C), maintenance, outcome (O), blinding techniques, time of study (T), and type of study (T).