====== PICO question ====== A PICO question is a structured clinical question used in evidence-based medicine to guide literature searches and decision-making. Here's what PICO stands for: P – Patient, Population, or Problem: Who is the patient or what is the condition? I – Intervention: What is the main treatment or diagnostic test being considered? C – Comparison: What is the alternative to compare with the intervention? (optional) O – Outcome: What are the relevant outcomes (e.g., survival, symptom relief, accuracy)? Example PICO question: Clinical Question: In adults with glioblastoma, does bevacizumab compared to temozolomide improve overall survival? PICO breakdown: P: Adults with glioblastoma I: Bevacizumab C: Temozolomide O: Overall survival