====== Peripheral nerve hyperexcitability ======

Peripheral nerve [[hyperexcitability]] (PNH) is a [[syndrome]] of spontaneous and continuous [[muscle fiber]] activity, [[cramp]]s, and slow relaxation of muscles of [[peripheral nerve]] origin. The electrophysiologic basis consists of spontaneous [[burst]]


Raja SN, Ringkamp M, Guan Y, Campbell JN. [[John J. Bonica]] Award Lecture: Peripheral neuronal hyperexcitability: the "low-hanging" target for safe therapeutic strategies in neuropathic pain. Pain. 2020 Sep;161 Suppl 1:S14-S26. doi: 10.1097/j.pain.0000000000001838. PMID: 33090736.s of single motor unit discharges with a high intraburst frequency.
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