====== Pedunculopontine nucleus ====== {{ ::pedunculopontinenucleus.jpg?400|}} The pedunculopontine tegmental nucleus (PPTg) is a component of the locomotor [[mesencephalic]] area. ====Location==== The pedunculopontine nucleus (PPN) (or pedunculopontine tegmental nucleus, PPTN or PPTg) is located in the [[brainstem]], caudal to the [[substantia nigra]] and adjacent to the [[superior cerebellar peduncle]]. It has two divisions, one containing cholinergic neurons, the pars compacta, and one containing mostly glutamatergic neurons, the pars dissipata. The PPN is one of the main components of the reticular activating system. The [[pedunculopontine nucleus]] was first described in [[1909]] by Louis Jacobsohn-Lask, a neuroanatomist born in Bydgoszcz. ===== Indications ===== ===== Pedunculopontine nucleus stimulation for progressive supranuclear palsy ===== [[Pedunculopontine nucleus stimulation for progressive supranuclear palsy]] ==== Deep Brain Stimulation of the Pedunculopontine Nucleus Area for Parkinson Disease ==== see [[Deep Brain Stimulation of the Pedunculopontine Nucleus Area for Parkinson Disease]]