====== Pediatric traumatic brain injury guidelines ====== see [[Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition]] In a [[systematic review]] and [[guideline]] appraisal for pediatric clinical practice guidelines (CPGs) concerning the acute management of [[Pediatric Traumatic Brain Injury]]. Targeted [[guideline]] creation specific to the [[pediatric]] population has the potential to improve the [[quality]] of acute [[TBI]] clinical practice guidelines (CPGs). Furthermore, it is crucial to address the applicability of a guideline to translate the CPG from a published manuscript into clinically relevant local practice tools and for resource limited practice settings ((Appenteng R, Nelp T, Abdelgadir J, Weledji N, Haglund M, Smith E, Obiga O, Sakita FM, Miguel EA, Vissoci CM, Rice H, Vissoci JRN, Staton C. A systematic review and quality analysis of pediatric traumatic brain injury clinical practice guidelines. PLoS One. 2018 Aug 2;13(8):e0201550. doi: 10.1371/journal.pone.0201550. eCollection 2018. PubMed PMID: 30071052; PubMed Central PMCID: PMC6072093. )). Guidelines for Diagnosing and Managing Pediatric Concussion [[https://onf.org/documents/guidelines-for-pediatric-concussion|Guidelines]]. ---- [[Thromboprophylaxis in Traumatic brain injury]]: [[Low-molecular-weight heparin]] (LMWH) prophylaxis in [[pediatric traumatic brain injury]] appears to be more effective than [[unfractionated heparin]] (UH) in preventing [[venous thromboembolism]] (VTE). Large, [[multicenter]] [[prospective]] studies are warranted to confirm the superiority of LMWH over UH in [[pediatric patient]]s with [[traumatic brain injury]]. Moreover, outcomes of VTE prophylaxis in the very young remain understudied; therefore, dedicated studies to evaluate this population are needed ((van Erp IA, Gaitanidis A, El Moheb M, Kaafarani HMA, Saillant N, Duhaime AC, Mendoza AE. Low-molecular-weight heparin versus unfractionated heparin in pediatric traumatic brain injury. J Neurosurg Pediatr. 2021 Feb 12:1-6. doi: 10.3171/2020.9.PEDS20615. Epub ahead of print. PMID: 33578391.)).