====== Pediatric low-grade glioma epidemiology ======

[[Pediatric low-grade glioma]]s are the most frequent [[pediatric brain tumor]]s; with countrywide registration in [[Germany]], they constitute 40–50 % of CNS tumors below the age of 18 years. Median age at diagnosis is around 6–8 years, and around 7 % of patients are younger than 1 year. All series confirm a small male preponderance with a sex ratio of 1.1–1.3:1 
((Gnekow AK, Falkenstein F, von Hornstein S et al. Long-term follow-up
of the multicenter, multidisciplinary treatment study HIT-LGG-1996
for low-grade glioma in children and adolescents of the German
Speaking Society of Pediatric Oncology and Hematology. Neurooncology 2012; 14: 1265–1284
))
((Stokland T, Liu JF, Ironside JW et al. A multivariate analysis of factors
determining tumor progression in childhood low-grade glioma: A
population-based cohort study (CCLG CNS9702). Neuro-oncology
2010; 12: 1257–1268)).