A [[cardiac pacemaker]], is a medical device that generates electrical impulses delivered by electrodes to cause the heart muscle chambers to contract and therefore pump blood; by doing so this device replaces and/or regulates the function of the electrical conduction system of the heart. ---- MR-guided focused ultrasound (MRgFUS) has proven its efficacy and safety for the treatment of essential tremor (ET) and/or Parkinson's disease (PD). However, having a cardiac pacemaker has been considered an exclusion criterion for the use of MRgFUS. Only 2 patients with a cardiac pacemaker treated with MRgFUS have been previously reported, both treated using 1.5-T MRI. In this paper, the authors present their experience performing 3-T MRgFUS thalamotomy in 4 patients with an implanted cardiac pacemaker. Treatments were uneventful regarding complications or severe side effects. MRgFUS using 3-T MRI was found to be an efficient and safe treatment for ET and/or PD in patients with an MRI-compatible pacemaker ((Gonzalez-Quarante LH, Gonzalez-Crespo A, Arcadi A, Macias-de-la-Corte M, Aviles-Olmos I, Sanchez-Catasus CA, Cacho-Asenjo E, Honorato-Cia C, Martinez-Simon A, Gorospe A, Martin-Bastida A, Corral-Alonso P, Rodriguez-Oroz MC, Guridi J. 3-T MR-guided focused ultrasound thalamotomy for tremor in patients with a cardiac pacemaker: case series and review of the literature. Neurosurg Focus. 2024 Sep 1;57(3):E5. doi: 10.3171/2024.6.FOCUS24171. PMID: 39217637.)) ---- 1: Huang MS, Su YH, Chen JY. Post cardiac injury syndrome successfully treated with medications: a report of two cases. BMC Cardiovasc Disord. 2021 Aug 14;21(1):394. doi: 10.1186/s12872-021-02200-5. PMID: 34391394. 2: Fujii M, Satow T, Kodama H, Horiguchi S. Severe hemodynamic depression after carotid artery stenting: The problem overcome with a transvenous temporary cardiac pacemaker. 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