[[Multiple Sclerosis]] (MS) is often accompanied by [[myelopathy]], which may be associated with progressive worsening. A specific finding of MS-associated myelopathy is [[McArdle sign]], wherein [[neck flexion]] is associated with prominent increased [[limb]] [[weakness]] relative to that detected with [[neck extension]]. In a study, Schilaty et al. characterized neuromotor control properties of finger extensors in association with the McArdle sign.