====== Multiplex ligation-dependent probe amplification ======

Findings suggest that [[G-banding]] is not a suitable test for [[1p/19q co-deletion]] analysis. Within these limits considering cost per diagnosis, and using [[FISH]] as a reference, [[Multiplex ligation-dependent probe amplification]] (MLPA) was marginally more [[cost-effective]] than other tests, although these economic analyses were limited by the range of available parameters, time horizon, and data from multiple health care organizations
((Brandner S, McAleenan A, Jones HE, Kernohan A, Robinson T, Schmidt L, Dawson S, Kelly C, Leal ES, Faulkner CL, Palmer A, Wragg C, Jefferies S, Vale L, P T Higgins J, Kurian KM. Diagnostic accuracy of [[1p/19q co-deletion]] tests in [[oligodendroglioma]]: a comprehensive [[meta-analysis]] based on a [[Cochrane]] [[Systematic Review]]. Neuropathol Appl Neurobiol. 2021 Dec 26. doi: 10.1111/nan.12790. Epub ahead of print. PMID: 34958131.)).