=====mir 1=====
Wang et al. investigated the effect of [[miR 1]] on human glioma by inhibiting the expression of miR-1. Anti-miR-1, an anti-sense oligonucleotide against miR-1, significantly reduced the level of miR-1 in the human glioma cell line U87 (P < 0.05). Further, cell proliferation and colony formation assays were used to determine the effect of miR-1 on cell growth. The scratch assay and cell migration assay were performed to evaluate cell invasion. 

Data demonstrated that the growth of glioma cells was impeded due to the decrease in miR-1 levels, compared to the untransfected control cells (P < 0.05). Interestingly, the invasion and mobility of the cells were also retarded after transfection with anti-miR-1 (P < 0.05). 

In conclusion, the results indicate that the down-regulation of miR-1 significantly inhibited cell proliferation and reduced cell motility, suggesting that anti-miR-1 could be used as a therapeutic intervention tool to counter the activity of neuroglioma cells
((Wang YQ, Cai Y, Zhong XM. Suppression of the biological activity of
neuroglioma cells by down-regulation of miR-1. Genet Mol Res. 2017 Aug 31;16(3). 
doi: 10.4238/gmr16039256. PubMed PMID: 28873202.)).

[[Pseudolaric acid B]] (PAB), a diterpene acid isolated from the root and trunk bark of Pseudolarix kaempferi Gordon (Pinaceae), was found to inhibit cell growth in a variety of cancer cell lines, but to date the effect of PAB on [[neuroglioma]] remains unclear.