====== Middle cerebral artery pathology ====== The [[middle cerebral artery]] is the [[artery]] most often occluded in [[stroke]]. Anatomical variations of the [[middle cerebral artery]] (MCA) are an important clinical issue, due to high [[prevalence]] of [[intracranial aneurysm]]s. Anatomical variations of [[vessel]]s can lead to higher [[wall shear stress]], which is thought to be the main factor leading to [[aneurysm]] formation and consequently to higher prevalence of aneurysms. The most common configuration of MCA is bifurcation before the genu with no dominating post-division trunk. Incidence of MCA aneurysms is not correlated with anatomical variations of MCA and the [[circle of Willis]] ((Brzegowy P, Polak J, Wnuk J, Łasocha B, Walocha J, Popiela TJ. Middle cerebral artery anatomical variations and aneurysms - retrospective study based on computed tomography angiography findings. Folia Morphol (Warsz). 2017 Dec 13. doi: 10.5603/FM.a2017.0112. [Epub ahead of print] PubMed PMID: 29235088. )). ===== Middle cerebral artery occlusion ===== see [[Middle cerebral artery occlusion]]. ===== Middle cerebral artery aneurysm ===== see [[Middle cerebral artery aneurysm]].