====== Middle cerebral artery aneurysm epidemiology ======

{{rss>https://pubmed.ncbi.nlm.nih.gov/rss/search/1RGmO3jHeXUy8p1_WkK9RHH3bHmHIUr84LTrWF4f0WdfXC3AiX/?limit=15&utm_campaign=pubmed-2&fc=20231108043621}}
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[[Middle cerebral artery aneurysm]]s, represent almost a third of all the [[intracranial aneurysm]]s of the [[anterior circulation aneurysm]]s. 18-40% of all [[intracranial aneurysm]]s
((Elsharkawy A, Lehečka M, Niemelä M, Billon-Grand R, Lehto H, Kivisaari R,
Hernesniemi J. A new, more accurate classification of middle cerebral artery
aneurysms: computed tomography angiographic study of 1,009 consecutive cases with
1,309 middle cerebral artery aneurysms. Neurosurgery. 2013 Jul;73(1):94-102;
discussion 102. doi: 10.1227/01.neu.0000429842.61213.d5. PubMed PMID: 23615110.
)).

Among them, those located at [[M1 segment of the middle cerebral artery]] (from its origin up to the bifurcation) range between 2% and 7% of all the aneurysms. 

Most MCA aneurysms have been found at the division of the M1-M2 junction due to hemodynamic stress or congenital factors
((Rinne J, Hernesniemi J, Niskanen M, Vapalahti M. Analysis of 561 patients with
690 middle cerebral artery aneurysms: anatomic and clinical features as
correlated to management outcome. Neurosurgery. 1996 Jan;38(1):2-11. PubMed PMID:
8747945.
)).


Only in 1.1-1.7% of cases they are located in the distal segment
((Ahn JY, Han IB, Joo JY. Aneurysm in the penetrating artery of the distal
middle cerebral artery presenting as intracerebral haemorrhage. Acta Neurochir
(Wien). 2005 Dec;147(12):1287-90; discussion 1290. Epub 2005 Aug 29. PubMed PMID:
16133768.
))
((Lv N, Zhou Y, Yang P, Li Q, Zhao R, Fang Y, Xu Y, Hong B, Zhao W, Liu J, Huang
Q. Endovascular treatment of distal middle cerebral artery aneurysms: Report of
eight cases and literature review. Interv Neuroradiol. 2016 Feb;22(1):12-7. doi: 
10.1177/1591019915617317. Epub 2015 Dec 3. Review. PubMed PMID: 26637241; PubMed 
Central PMCID: PMC4757379.
))
((Elsharkawy A, Lehečka M, Niemelä M, Billon-Grand R, Lehto H, Kivisaari R,
Hernesniemi J. A new, more accurate classification of middle cerebral artery
aneurysms: computed tomography angiographic study of 1,009 consecutive cases with
1,309 middle cerebral artery aneurysms. Neurosurgery. 2013 Jul;73(1):94-102;
discussion 102. doi: 10.1227/01.neu.0000429842.61213.d5. PubMed PMID: 23615110.
)).

The majority of distal MCA aneurysms are located at the M2 or M3 segments
((Lee SH, Bang JS. Distal Middle Cerebral Artery M4 Aneurysm Surgery Using
Navigation-CT Angiography. J Korean Neurosurg Soc. 2007 Dec;42(6):478-80. doi:
10.3340/jkns.2007.42.6.478. Epub 2007 Dec 20. PubMed PMID: 19096593; PubMed
Central PMCID: PMC2588183.)).

===== References =====