====== Mesial temporal sclerosis ====== [[Mesial]] temporal [[sclerosis]] (MTS) is a term used to describe scarring in the deep part of the [[temporal lobe]]. ---- Mesial temporal sclerosis (MTS) is the most common cause of intractable [[temporal lobe epilepsy]]. ===== Etiology ===== see [[Mesial Temporal Sclerosis Etiology]]. ===== Pathology ===== The hippocampal formation is not uniformly affected, with the [[dentate gyrus]], and the [[CA1]], [[CA4]] and to a lesser degree [[CA3]] sections of the hippocampus being primarily involved. Histologically there is neuronal cell loss, gliosis and sclerosis. ===== Clinical Features ===== [[Mesial Temporal Sclerosis Clinical Features]]. ===== Diagnosis ===== [[Mesial Temporal Sclerosis Diagnosis]]. ===== Complications ===== Mesial temporal sclerosis (MTS) is the most common cause of intractable [[temporal lobe epilepsy]]. ===== Treatment ===== [[Mesial Temporal Sclerosis Treatment]].