====== Medulloblastoma clinical features ====== Clinical history is typically brief (6–12 weeks). The predilection for [[posterior fossa]] predisposes to early [[obstructive hydrocephalus]]. Usual presenting symptoms: H/A, N/V, and [[ataxia]]. Infants with hydrocephalus may present with irritability, lethargy, or progressive [[macrocrania]] ((Park TS, Hoffman HJ, Hendrick EB, et al. Medulloblastoma: Clinical Presentation and Management. J Neurosurg. 1983; 58:543–552)). Spinal drop metastases may produce [[back pain]], [[urinary retention]], or leg [[weakness]]. Common signs: [[papilledema]], truncal & appendicular [[ataxia]], [[nystagmus]], EOM palsies. Macrocrania in infants and young children. ---- [[Medulloblastoma]] may also cause nuclear [[facial palsy]] (from the involvement of [[facial colliculus]] on the floor of the [[fourth ventricle]]).