====== Marchiafava-Bignami Disease ====== [[Marchiafava–Bignami disease]] is a progressive neurological disease of [[alcoholism]], characterized by [[corpus callosum]] demyelination and [[necrosis]] and subsequent atrophy. The disease was first described in [[1903]] by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker. Refractory Nonconvulsive Status Epilepticus with Favorable Outcome in a Patient with Marchiafava-Bignami Disease ((Kim R, Cho HJ, Lee HW, Jun JS. Refractory Nonconvulsive Status Epilepticus with Favorable Outcome in a Patient with Marchiafava-Bignami Disease. J Clin Neurol. 2019 Mar 11. [Epub ahead of print] PubMed PMID: 30877698. )).