====== Malignant primary brain tumor ====== [[Glioblastoma]] (GBM) represents 47.1% of malignant [[primary brain tumor]]s, making it the most common type of malignant primary [[brain tumor]] ((Ostrom QT, Gittleman H, Liao P, Vecchione-Koval T, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS. [[CBTRUS]] Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010-2014. Neuro Oncol. 2017 Nov 6;19(suppl_5):v1-v88. doi: 10.1093/neuonc/nox158. PubMed PMID: 29117289; PubMed Central PMCID: PMC5693142. )). Incidence of [[primary central nervous system lymphoma]] ([[PCNSL]]) in the U.S.: 0.44 per 100,000, making it the third most common of malignant primary brain tumors (behind [[GBM]] & [[diffuse astrocytoma]]) ((Ostrom QT, Gittleman H, Liao P, Vecchione-Koval T, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS. [[CBTRUS]] Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010-2014. Neuro Oncol. 2017 Nov 6;19(suppl_5):v1-v88. doi: 10.1093/neuonc/nox158. PubMed PMID: 29117289; PubMed Central PMCID: PMC5693142. )).