====== Malignant hyperthermia treatment ====== 1. eliminate offending agents (stop the operation, D/C inhalation anesthesia and change tubing on anesthesia machine) 2. [[dantrolene]] sodium (Dantrium®) 2.5 mg/kg IV usually effective, infuse until symptoms subside, up to 10 mg/kg 3. [[hyperventilation]] with 100% O2 4. surface and cavity cooling: IV, in the wound, per NG, PR 5. bicarbonate 1–2 mEq/kg for acidosis 6. IV insulin and glucose (lowers K+, glucose acts as energy substrate) 7. procainamide for arrhythmias 8. diuresis: volume loading + osmotic diuretics ===== Dantrolene ===== see [[Dantrolene for malignant hyperthermia treatment]].