====== Macroencephaly ======

AKA macrencephaly, AKA megalencephaly. Not to be confused with [[macrocephaly]], which is an enlargement of the skull. Not a single pathologic entity. An enlarged brain may be due to hypertrophy of [[gray matter]] alone, gray and white matter, presence of additional structures (glial overgrowth, diffuse gliomas, heterotopias, metabolic storage diseases...).

Conditions in which macrocephaly may be seen include:

● neurocutaneous syndromes (especially [[neurofibromatosis]])

● megalencephaly-capillary malformation syndrome (MCAP): an overgrowth syndrome with [[megalencephaly]] (often with hydrocephalus, Chiari malformation, polymicrogyria, and seizures) and capillary malformations in the skin (usually on the face).