====== Loin Pain Hematuria Syndrome ======
Loin Pain [[Hematuria]] [[Syndrome]] (LPHS) is a rare condition characterized by [[cryptogenic]] debilitating [[flank pain]] and microscopic or macroscopic hematuria. 

===== Pathophysiology =====

The [[pathophysiology]] of LPHS remains poorly understood and [[diagnosis]] is made largely by exclusion of alternate pathology. 

===== Treatment =====

Management strategies can vary widely and include chronic [[opioid]] medication and a variety of invasive procedures including regional [[nerve block]]s, [[transcutaneous electrical nerve stimulation]], local [[capsaicin]] infusion, and surgical [[renal denervation]]. [[Neuromodulation]] may provide a new paradigm of treatment for LPHS, potentially sparing patients from long term [[complication]]s of opiate therapy and invasive surgery. 

A report of Richter et al. from  the Department of Neurosurgery, [[Allegheny General Hospital]], demonstrates the first case of successful symptomatic management of LPHS using [[spinal cord stimulation]]
((Richter B, Bergman J, Pierre J, Tomycz ND. Spinal Cord Stimulation for Loin
Pain Hematuria Syndrome: Case Report. Pain Pract. 2018 Dec 16. doi:
10.1111/papr.12755. [Epub ahead of print] PubMed PMID: 30554461.
)).