====== Knosp Grade 3B ======

===== Latest articles =====
{{rss>https://pubmed.ncbi.nlm.nih.gov/rss/search/1lqZ3NPYyseEVKt2tdzGgzqviLH2BMX8PQM-YhAy9ZIR3dgEt7/?limit=15&utm_campaign=pubmed-2&fc=20221201102147}}

{{::knosp_grade_3b.jpg?200|}}

Below the intracavernous [[internal carotid artery]] into the inferior [[cavernous sinus]] compartment
The tumor extends to the lateral line inferiorly (under [[ICA]])
((Micko AS, Wöhrer A, Wolfsberger S, Knosp E. Invasion of the cavernous sinus
space in pituitary neuroendocrine tumors: endoscopic verification and its correlation with an 
MRI-based classification. J Neurosurg. 2015 Apr;122(4):803-11. doi:
10.3171/2014.12.JNS141083. Epub 2015 Feb 6. PubMed PMID: 25658782.
)).
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A significantly higher rate of [[remission]] can be achieved in grade 3A than in grade 3B and grade 4 adenomas. Therefore, the distinction into grades 3A, 3B, and 4 is of importance for the [[prediction]] of [[adenoma]] invasion and surgical treatment considerations
((Micko A, Oberndorfer J, Weninger WJ, Vila G, Höftberger R, Wolfsberger S, Knosp E. Challenging Knosp high-grade pituitary neuroendocrine tumors. J Neurosurg. 2019 May 31;132(6):1739-1746. doi: 10.3171/2019.3.JNS19367. PMID: 31151112.))