=====Jugulotympanic paraganglioma=====
Jugulotympanic [[paraganglioma]]s (JTPs) are rare [[benign tumor]]s whose [[surgical treatment]] is usually associated with [[partial resection]], high [[morbidity]], and even [[death]]. 

====Treatment====
[[Gamma Knife radiosurgery]] (GKRS) has been reported as a useful treatment option. 

A total of 75 patients with JTPs were treated with GKRS from 1995 to 2012. Gandía-González et al., analyzed those treated during this period to allow for a minimal observation time of 2 years. The [[MR]] images and clinical reports of these patients were reviewed to assess clinical and volumetric outcomes of the tumors. The radiological and clinical assessments, along with a group of prognostic factors measured, were analyzed using descriptive methods. The time to volumetric and clinical progression was analyzed using the Kaplan-Meier method. Prognostic factors were identified using log-rank statistics and multivariate Cox regression models. 

The mean follow-up was 86.4 months. The authors observed volumetric tumor control in 94.8% of cases. In 67.2% of cases, tumor volume decreased by a mean of 40.1% from the original size. Of patients with previous tinnitus, 54% reported complete recovery. Improvement of other symptoms was observed in 34.5% of cases. Overall, clinical control was achieved in 91.4% of cases. Previous [[embolization]] and familial history of paraganglioma were selected as significant prognostic factors for volumetric response to GKRS treatment in the univariate analysis. In multivariate analysis, no factors were significantly correlated with [[progression free survival]]. No patient died of side effects related to GKRS treatment or tumor progression. 

Gamma Knife radiosurgery is an effective, safe, and efficient therapeutic option for the treatment of these tumors as a first-line treatment or in conjunction with traditional surgery, [[endovascular treatment]], or conventional fractionated radiotherapy
((Gandía-González ML, Kusak ME, Moreno NM, Sárraga JG, Rey G, Alvarez RM.
Jugulotympanic paragangliomas treated with Gamma Knife radiosurgery: a
single-center review of 58 cases. J Neurosurg. 2014 Nov;121(5):1158-65. doi:
10.3171/2014.5.JNS131880. Epub 2014 Jun 13. PubMed PMID: 24926654.
)).