=====Intrarterial chemotherapy===== Is a viable methodology in [[recurrent glioblastoma]] patients to prolong survival at the risk of procedure-related complications and in newly diagnosed patients with the benefit of decreased complications ((Theodotou C, Shah AH, Hayes S, Bregy A, Johnson JN, Aziz-Sultan MA, Komotar RJ. The role of intra-arterial chemotherapy as an adjuvant treatment for glioblastoma. Br J Neurosurg. 2014 Jan 16. [Epub ahead of print] PubMed PMID: 24432794.)).