The mean age at onset of symptoms in the Masri et al. cohort of 19 children was 6 years (range: 7 months to 12 years). Most patients (90%) were under 11 years old and (84.2%) symptomatic. The probable cause was identified in 7/19 (37.0%) patients. The most common cause was vitamin D deficiency (26.3%). Other associated probably coincidental comorbidities included sinusitis (5/19, 26.3%), hypophosphatasia (1/19), Pyle disease (1/19), and measles vaccine (1/19). Apart from 2 patients who required [[lumboperitoneal shunt]], the [[cerebrospinal fluid]] pressure returned to normal in all patients within a period of 6 weeks to 1 year (average, 5 months). Of those who followed up with the authors' ophthalmologist, 30.7% developed [[optic nerve]] [[atrophy]] or pallor; 75% of these patients had previous ocular comorbidities
((Masri A, Jaafar A, Noman R, Gharaibeh A, Ababneh OH. Intracranial Hypertension
in Children: Etiologies, Clinical Features, and Outcome. J Child Neurol. 2015 Mar
11. pii: 0883073815574332. [Epub ahead of print] PubMed PMID: 25762586.)).

Raised intracranial pressure (ICP) is recognized to occur in patients with nonsyndromic isolated [[sagittal craniosynostosis]] (SC) prior to surgery.