===== Intracerebral Hemorrhage Mortality ===== **Intracerebral hemorrhage (ICH)** is associated with **high early mortality** and poor long-term outcomes, making it one of the deadliest types of stroke. ==== Early Mortality ==== * **30-day mortality**: ~**35–50%** * Most deaths occur in the first 2 days, often due to hematoma expansion, herniation, or brainstem involvement. * **In-hospital mortality**: ~**20–30%**, depending on hematoma volume, location, and patient comorbidities. * **Higher mortality** seen in: * Brainstem and cerebellar hemorrhages * Large hematomas (>30–60 mL) * Intraventricular extension * Depressed level of consciousness at admission (GCS < 8) ==== Long-Term Outcomes ==== * **1-year survival**: ~**35–40%** * Only **10–20%** of survivors regain **functional independence** (modified Rankin Score ≤2). * Risk of death remains elevated for months due to recurrent stroke, infections, and comorbid conditions. ==== Predictors of Mortality ==== * Age > 80 years * Low Glasgow Coma Scale at presentation * Large hematoma volume * Infratentorial location * Intraventricular hemorrhage * High blood pressure on admission * Lack of early surgical or ICU management when indicated ==== Prognostic Tools ==== * [[ICH Score]]: validated clinical tool to estimate 30-day mortality based on: * GCS * Age * Hematoma volume * Intraventricular extension * Infratentorial origin ==== Related Sections ==== * [[Intracerebral hemorrhage definition]] * [[ICH Score]] * [[Intracerebral hemorrhage management]] ---- [[PM2.5]] [[exposure]]—particularly household-related in low [[Socio-demographic Index]] regions—continues to drive significant [[intracerebral hemorrhage mortality]] and morbidity despite global reductions in age-standardized rates. Disparities persist, with low SDI areas experiencing a 24.7-fold higher ASMR than high SDI regions. Projections indicate a resurgence in PM2.5-related ICH burden by 2050, emphasizing the need for tailored public health interventions targeting APMP and HAP, especially in Asia and Sub-Saharan Africa ((Wu E, Su R, Tang T, Zhu G, Geng D. Ambient versus household PM2.5 exposure and socioeconomic disparities in intracerebral hemorrhage burden: a 32-year global analysis (1990-2021) with projections to 2050. Front Public Health. 2025 Jun 18;13:1615934. doi: 10.3389/fpubh.2025.1615934. PMID: 40606082; PMCID: PMC12213839.))