====== In vitro ======


In vitro studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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A standardized in vitro [[model]] helps to objectify the [[Water-tight]]ness of [[dural closure]]. It allows testing of sutures and dural grafts alone or in combination. In the authors' testing, a running 6-0 monofilament polypropylene suture combined with [[DuraSeal]] or [[TachoSil]] was the technique achieving the highest BP. For the [[duraplasty]] of square defects, the double-layer technique showed the highest efficacy.