The [[femoral artery]] is the most common access route for [[cerebral angiography]] and [[neurointervention]]al [[procedure]]s. [[Complication]]s of the [[transfemoral]] [[approach]] include [[groin]] [[hemorrhage]]s and [[hematoma]]s, [[retroperitoneal hematoma]]s, [[pseudoaneurysm]]s, [[arteriovenous fistula]]s, [[peripheral artery]] occlusions, [[femoral nerve injury]], and access-site [[infection]]s. [[Incidence]] [[rate]]s vary among different [[randomized]] and nonrandomized [[trial]]s, and the [[literature]] lacks a [[comprehensive review]] of this subject.

Oneissi et al. gather data from 16 [[randomized clinical trial]]s (RCT) and 17 nonrandomized [[cohort]] studies regarding femoral access-site complications for a review [[paper]]. They also briefly discussed [[management]] strategies for these [[complication]]s based on the most recent [[literature]].

A [[PubMed]] indexed search for all [[neuroendovascular]] [[clinical trial]]s, [[retrospective]] studies, and [[prospective]] studies that reported femoral artery access-site complications in neurointerventional procedures.

The overall access-site complication rate in RCTs is 5.13%, while in non-RCTs, the rate is 2.78%. The most common complication in both groups is [[groin hematoma]] followed by access-site hemorrhage and [[femoral artery pseudoaneurysm]]. On the other hand, [[wound infection]] was the least common complication.

The [[transfemoral]] approach in [[neuroendovascular]] [[procedure]]s holds risk for several complications. This review will allow further studies to compare access-site complications between the transfemoral approach and other alternative access sites, mainly the [[trans-radial artery approach]], which is gaining a lot of interest nowadays
((Oneissi M, Sweid A, Tjoumakaris S, Hasan D, Gooch MR, Rosenwasser RH, Jabbour 
P. Access-Site Complications in Transfemoral Neuroendovascular Procedures: A
Systematic Review of Incidence Rates and Management Strategies. Oper Neurosurg
(Hagerstown). 2020 May 4. pii: opaa096. doi: 10.1093/ons/opaa096. [Epub ahead of 
print] PubMed PMID: 32365203.
)).