====== Genetic profile ======

The term genetic profile is generally used to denote genetic signatures or information as a combination of genetic characteristics related to a human being.

see [[DNA profiling]]
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Recent developments in [[radiomics]] based image analysis have enabled new possibilities to non-invasively determine the [[histopathology]] and/or [[genetic profile]] of a number of different tumor entities 
((Lohmann P, Galldiks N, Kocher M, Heinzel A, Filss CP, Stegmayr C, Mottaghy FM, Fink GR, Jon Shah N, Langen KJ. Radiomics in neuro-oncology: Basics, workflow, and applications. Methods. 2021 Apr;188:112-121. doi: 10.1016/j.ymeth.2020.06.003. Epub 2020 Jun 6. PMID: 32522530.)).

This is especially important for cerebral [[glioma]]s, as the latest [[WHO]] classification of [[2016]] puts the focus on the genetic profile to classify [[tumor]]s precisely and plan [[personalized therapy]] regimens accordingly
((Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The [[2016]] [[World Health Organization]] [[Classification]] of [[Tumor]]s of the [[Central Nervous System]]: a summary. Acta Neuropathol. 2016 Jun;131(6):803-20. doi: 10.1007/s00401-016-1545-1. Epub 2016 May 9. PMID: 27157931.)).