====== Generalized epilepsy ====== Generalized epilepsy is a type of epilepsy in which seizures appear to originate simultaneously in both hemispheres of the brain. The **International League Against Epilepsy (ILAE)** provides a classification system that helps clinicians describe and categorize epilepsy types more precisely. ### 🔷 **Generalized Epilepsy: ILAE 2017 Classification** #### ✅ **1. Generalized Seizure Types** These are seizure types that start in both hemispheres at once: - **Generalized Tonic-Clonic Seizures (GTCS)** ➤ Convulsions with stiffening (tonic) and jerking (clonic) phases. - **Absence Seizures** ➤ Brief lapses in consciousness (e.g., staring spells). Subtypes: - Typical - Atypical - Myoclonic absence - Eyelid myoclonia - **Myoclonic Seizures** ➤ Sudden, brief muscle jerks, often in the arms or shoulders. - **Tonic Seizures** ➤ Sustained muscle stiffening, typically during sleep. - **Atonic Seizures** ➤ Sudden loss of muscle tone, causing drop attacks. - **Clonic Seizures** ➤ Rhythmic jerking movements (rare in isolation in generalized epilepsy). #### ✅ **2. Generalized Epilepsy Syndromes** These are broader syndromes that include multiple seizure types and typically have a known electroclinical pattern: - **Childhood Absence Epilepsy (CAE)** - **Juvenile Absence Epilepsy (JAE)** - **Juvenile Myoclonic Epilepsy (JME)** - **Epilepsy with Generalized Tonic-Clonic Seizures Alone** - **Lennox-Gastaut Syndrome (LGS)** – although often considered combined generalized and focal - **Dravet Syndrome** – also has generalized and focal components #### ✅ **3. Etiological Classification** ILAE recommends classifying the **cause** of generalized epilepsy under one or more of the following categories: - **Genetic** (e.g., [[idiopathic generalized epilepsy]], JME) [[Genetic generalized epilepsy]] - **Structural** (less common in generalized forms) - **Metabolic** - **Immune** - **Infectious** - **Unknown** #### ✅ **4. EEG Findings** - Generalized spike-and-wave or polyspike-and-wave discharges - Bilaterally synchronous - Normal background (in idiopathic types)