[[​​GABA]]ergic [[neuron]]s produce gamma-Aminobutyric acid (GABA), which is the main inhibitory [[neurotransmitter]] in the mammalian central nervous system (CNS). GABA is primarily synthesized from [[glutamate]], catalyzed by glutamate decarboxylase (GAD), and is present at 30 - 40% of synapses.