=====G protein coupled receptor=====

(GPCRs) which are also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and [[G protein]]–linked receptors (GPLR), constitute a large protein family of receptors, that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times

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[[Frizzled]] is a family of [[G protein coupled receptor]] proteins that serves as receptors in the [[Wnt signaling pathway]] and other [[signaling pathway]]s. When activated, Frizzled leads to activation of [[Dishevelled]] in the cytosol.

see [[GPR65]].