Intra-articular [[facet injection]]s of [[hypertonic saline]] and subsequent pain reproduction was performed by Hirsch in [[1963]] ((HIRSCH C, INGELMARK BE, MILLER M. The anatomical basis for low back pain. Studies on the presence of sensory nerve endings in ligamentous, capsular and intervertebral disc structures in the human lumbar spine. Acta Orthop Scand. 1963;33:1-17. PubMed PMID: 13961170. )) supporting the role of [[facet joint]]s in [[lower back pain]].