====== Epidural analgesia ====== Spinal dorsal [[instrumentation]] (SDI) is an established treatment for [[degenerative]] [[spinal disease]]s. Adequate and immediate [[postoperative]] [[pain]] control is important for the patient [[recovery]] and may be compromised by uncertainty about its [[efficacy]] and concern about early postoperative surgical [[complication]]s or [[adverse event]]s. ---- The aim of the study was to compare the use of epidural [[analgesia]] (EA) with systemic analgesia (SA) as regards pain reduction and early postoperative complications after SDI. [[Pain management]] with epidural or systemic analgesia in patients undergoing SDI by posterior approach between January 2019 and July 2020 was evaluated by clinical functional testing, measuring total opioid amounts used, and evaluating numerical rating scale values 24 and 96 hours postoperatively. The following were also monitored: demographic data, number of affected segments, length of hospital stay, inflammatory markers (leukocytes and serum C-reactive protein), early postoperative surgical complication rates, and adverse events. In total 79 patients were included (33 in the EA and 46 in the SA group). The SA group had significantly lower numerical rating scale values at days 1 to 4 after surgery (P ≤ .001) and lower cumulative opioid use than the EA group (P < .001). We found no difference in infection parameters, length of hospital stay or surgery-related complication rates. Our data demonstrate that epidural anesthesia was inferior to an opioid-based SA regime in reducing postoperative pain in patients undergoing spinal surgery. There is no benefit to the use of epidural catheters ((Hamed M, Asoglu H, Lampmann T, Winkelmann LM, Salemdawod A, Müller M, Vatter H, Banat M, Eichhorn L. Pain management with epidural catheter and epidural analgesia after spinal dorsal instrumentation of lumbar spine. Medicine (Baltimore). 2023 Feb 17;102(7):e32902. doi: 10.1097/MD.0000000000032902. PMID: 36800634; PMCID: PMC9936043.))